Casa Loma has served as a dramatic backdrop for many television commercials. The following brands and organizations have filmed commercials at the castle:
- Honey Nut Cheerios
- Cool Whip
- Toblerone
- Wunderbar
- Royal Bank
- Jenny Craig
- London Life
- Leons
- Ontario Jockey Club
- Ontario Government
- Ontario Lottery
- Harlequin Romance
- Doc Otis
- The History Channel
- Advil
- Blue Cross